antiviral

1. IntroductionHepatitis B virus (HBV) infection is a serious global health problem, and chronic HBV infection significantly increases the risk of liver fibrosis, cirrhosis, and even hepatocellular carcinoma (HCC) in patients . The…

Graphical abstract. Credit: Journal of Controlled Release (2023). DOI: 10.1016/j.jconrel.2023.12.031 A team from Houston Methodist…

Antiviral Drugs While getting an influenza (flu) vaccine each year is recommended by CDC as the first and most important step in protecting against flu, there also are drugs that can treat flu illness. These “flu antiviral drugs” are an…

1. IntroductionViruses must overcome the barriers of host defense mechanisms to establish a successful infection. The first line of intracellular protection, known as intrinsic immunity, is exerted by so-called restriction factors…

1. IntroductionThroughout history, mankind has been afflicted by many infectious diseases, often associated with outbreaks and pandemics with devastating results, leading to economic crisis and disruption of public health systems. Among…

Methods Study Cohort and Patient Characteristics Data on vaccination and SARS-CoV-2 infection and demographic and clinical data were obtained from the VA COVID-19 Shared Data Resource (7) and from electronic medical records (EMRs) and…

What GAO Found Antiviral drugs help the body fight off harmful viruses and can ease symptoms and shorten the length of an infection. Some of these drugs can be broadly acting—that is, they can treat infections from multiple…

1. IntroductionGlobally, an estimated 257 million individuals are chronically infected with hepatitis B virus (HBV), which can progress to liver cirrhosis and hepatocellular carcinoma (HCC) . Current approved therapies using pegylated…

1. IntroductionLooking through the historical lens, every few decades human health has faced epidemic diseases that seriously endanger human life . Viral infection on a population scale is one of the oldest risks that always emerge with…

In this study, we investigated the applicability of HBcrAg for monitoring during and after antiviral treatment in patients with chronic hepatitis B and chronic HBV infection. We demonstrated that during treatment with NA, both levels of…

LEXINGTON, Ky. (April 2, 2020) — Dibakar Bhattacharyya has been a fixture in the University of Kentucky’s College of Engineering for more than 50 years and is renowned for his research, which focuses on incorporating life sciences…

1. IntroductionAccording to the Centers for Disease Control and Prevention (CDC), one of the major neurologic Long COVID sequelae is anosmia, which has a significant negative impact on patients’ quality of life . Recently published…

LEXINGTON, Ky. (July 20, 2022) — A team of University of Kentucky researchers led by College of Engineering Professor Dibakar Bhattacharyya, Ph.D., and his Ph.D. student, Rollie Mills, have developed a medical face mask membrane that can…

By combining nanotechnology with antiviral substances, researchers have developed new synthetic membranes that can deactivate the SARS-CoV-2 virus responsible for the COVID-19 pandemic. These sophisticated materials also filter the virus…

Infectious Disease Reports, Vol. 16, Pages 65-82: Management of Cytomegalovirus Infections in the Era of the Novel Antiviral Players, Letermovir and Maribavir Infectious Disease Reports doi: 10.3390/idr16010005 Authors: Jocelyne…

December 9, 2022—Flu season came early this year with some of the highest hospitalization rates seen at this time of the year in a decade. Preliminary data from CDC indicate that so far this season, nearly 50% of reported flu-associated…

January 11, 2023—CDC’s latest flu vaccination coverage estimates were updated on January 6, 2023. Estimates show that a drop in flu vaccine uptake observed early this season among adults overall has narrowed as the season has progressed;…

2. The Applications of Nanoparticles in Influenza VaccinesInfluenza is an acute respiratory infection caused by the influenza virus, which often occurs in the form of seasonal epidemics. It is a highly infectious and rapidly spreading…

February 22, 2023—This year’s flu vaccines reduced the risk of influenza A-related hospitalization among children by nearly three quarters and among adults by nearly half according to CDC. Vaccination also provided significant protection…

February 25, 2023 — Two human infections with avian influenza A H5N1 (H5N1 bird flu) virus have been reported by Cambodia. These cases are thought to be a result of exposure to infected birds/poultry. An investigation to try to confirm…

April 14, 2023— The National Health Commission of the People’s Republic of China reported a confirmed case of human infection with avian influenza A(H3N8) virus “H3N8 bird flu” on March 27, 2023. The patient was an adult with multiple…

This week, CDC staff will be convening with leaders from animal and human health sectors across Southeast Asia to hone avian influenza (bird flu) preparedness in the region. The main purpose of this workshop is to share best practices in…

As flu activity in the United States continues at low levels that are typical for this time of year, CDC also is tracking flu activity in the Southern Hemisphere, which generally has its “flu season” at this time. Surveillance data show…

On June 21, 2022, this report was posted online as an MMWR Early Release.Summary What is already known about this topic? Lagevrio and Paxlovid are oral antiviral drugs effective at preventing hospitalization and death in patients with…

Equitable access to COVID-19 therapeutics is a critical aspect of the distribution program led by the U.S. Department of Health and Human Services (HHS).* Two oral antiviral products, nirmatrelvir/ritonavir (Paxlovid)† and molnupiravir…

by Angharad Brewer Gillham, Frontiers science writer Image/Shutterstock.com Scientists have found that specially processed samples of willow bark extract have an antiviral effect which isn’t seen in already known medical…

A drug developed for smallpox was given to a person with monkeypox in 2021, and it seemed to shorten their illness compared with…

FluSurv-NET A total of 2,339 laboratory-confirmed influenza-associated hospitalizations were reported by FluSurv-NET sites between October 1, 2021, and April 2, 2022. The overall cumulative hospitalization rate was 8.0 per 100,000…