cell

1. IntroductionThe T cell engager (TCE), which redirects cytotoxic T cells to kill tumor cells, is emerging as a promising strategy to treat cancer patients, especially those with a low-mutation-burden tumor or a low number of…

The 2021 Dr. Martin Rodbell Lecture Series Seminar was a virtual event and featured Aviv Regev, Ph.D., Genentech executive vice president of research and early development (see first sidebar). She delivered her talk, 'Cell Atlases as…

1. IntroductionScabies is a contagious skin disease caused by the mite Sarcoptes scabiei var. hominis, an obligate ectoparasite that infects the epidermis of the human skin. Clusters of scabies are common among vulnerable populations in…

Author ContributionsAll authors contributed to the study conception and design. Conceptualization: K.-i.N.; Formal analysis: M.H., T.T., M.K., T.F., M.T., and H.S.; Funding acquisition: K.-i.N.; Investigation: M.H., S.S., N.U., T.T., and…

This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Vaccines 2024, 12(4), 368; https://doi.org/10.3390/vaccines12040368 (registering DOI) Submission received: 15 February 2024 / Revised:…

DUBLIN--(BUSINESS WIRE)--The "Global Cell Counting Market: Analysis By Product, By Application, By End-User, By Region Size, Trends and Forecast to 2029" report has been added to ResearchAndMarkets.com's offering. The global cell…

slc43a2+ T cells differentiate and mature in spleen and are then transported to brain to trigger the production of cytokines involved in antiviral strategies…

Credit: Pixabay/CC0 Public Domain New research presented early ahead of this year's European Congress of Clinical Microbiology and…

SEATTLE--(BUSINESS WIRE)-- #AGBT2024--NanoString Technologies, Inc. (OTC: NSTGQ), a leading provider of life science tools for discovery and translational research, today announced that research using the company’s CosMx™ Spatial…

SHANGHAI & CAMBRIDGE, Mass.--(BUSINESS WIRE)--Zai Lab Limited (Nasdaq: ZLAB; HKEX: 9688) partner Novocure (NASDAQ: NVCR) today announced the phase 3 METIS clinical trial met its primary endpoint, demonstrating a statistically…

EMERYVILLE, Calif.--(BUSINESS WIRE)--In response to strong customer demand, Slingshot Biosciences is introducing a groundbreaking portfolio of products that will transform the landscape of analytical precision in cell therapy. Its first…

This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Open AccessReview by Eleftheria KampouriEleftheria Kampouri 1,*, Guy HandleyGuy Handley Dr. Guy Handley is an Assistant Professor…

Start Preamble National Institutes of Health, HHS.…

This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Biomedicines 2024, 12(3), 703; https://doi.org/10.3390/biomedicines12030703 (registering DOI) Submission received: 30 January 2024 /…

1. IntroductionIn the pursuit of sustainable energy solutions, photovoltaic (PV) technology has become a cornerstone in the transition to renewable power sources. The adoption of solar panels promises reduced carbon footprints and…

REDWOOD CITY, Calif.--(BUSINESS WIRE)--Arcellx, Inc. (NASDAQ: ACLX), a biotechnology company reimagining cell therapy through the development of innovative immunotherapies for patients with cancer and other incurable diseases, today…

In the current retrospective analysis, we tried to simulate the control group of the PACIFIC study and test for differences in the OS relative to PD-L1 expression. No differences in the OS between PD-L1 <1% and ≥1% were found.Also, no…

1. IntroductionOral squamous cell carcinoma (OSCC) is a malignant epithelial tumor arising from the mucosal surfaces of the oral cavity. Despite advances in treatment, OSCC continues to have poor survival rates, with a 5-year survival…

Author ContributionsM.G.: Conceptualization, Methodology, Data Curation, Investigation, Writing—Original Draft, Data Curation, Resources, Preparation, Supervision, Project administration, Revision; C.P.: Data Curation, Resources,…

This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Biology 2024, 13(3), 191; https://doi.org/10.3390/biology13030191 (registering DOI) Submission received: 13 February 2024 / Accepted: 15…

The first trial ever of a former president, the so-called “hush money” case against former president and likely GOP presidential nominee Donald Trump, is scheduled to begin with jury selection in New York on March 25, 2024, though…

1. IntroductionThyroid cancer (TC) is the most frequently diagnosed endocrine-related malignancy, accounting for about 3–4% of all human cancers . Based on its histology, TC originating from follicular cells can be classified as either…

1. IntroductionChina announced its carbon emission targets, aiming to achieve “carbon peak” and “carbon neutrality” by 2030 and 2060, respectively. To fulfill these “dual carbon” objectives, while also taking into account the bottom-up…

Hemoglobin types and sickle cell disease   Your red blood cells contain hemoglobin, a protein that carries oxygen. Red blood cells need hemoglobin to deliver oxygen to your body’s organs and tissues. Every red blood cell…

Hemoglobin types and sickle cell disease   Your red blood cells contain hemoglobin, a protein that carries oxygen. Red blood cells need hemoglobin to deliver oxygen to your body’s organs and tissues. Every red blood cell…

This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Open AccessArticle by 1,2,*,†, 3,4,†, 1, Karina Sif Soendergaard Mosholt 5, 6, 7, 8, 6, 2,7,9, 10 and 3,4 1…

Electricity and heat generation are the largest sources of global greenhouse gas emissions worldwide, accounting for about 55% . The residential sector accounts for 39% of global final energy consumption in buildings and industry . The…

We read with great interest the “Update: Cold Weather Injuries Among the Active and Reserve Components of the U.S. Armed Forced, July 2018-June 2023.”1 While the update provides valuable insight into the relative number of…

Recognizing age as a pivotal risk factor for age-associated diseases, particularly neurodegenerative diseases (ND), such as Alzheimer's disease (AD) (Peng et al., 2021) and Parkinson's disease (PD), underscores the urgency of…

1. IntroductionFor patients with metastatic penile squamous cell carcinoma (PSCC), the median survival time is 1]. The overall response rate to common first-line combination chemotherapy treatments such as paclitaxel, ifosfamide, and…

The complex relationship between environmental stressors, extracellular vesicles (EVs), and adverse health outcomes was the focus of an NIEHS workshop held Sept. 27-28. Shaughnessy manages grants on the development and validation of…

In the original publication , there was an honest mistake in Figure 4D (P-AKT panel) as published. The P-AKT expression was erroneously duplicated from Figure 5D. The corrected Figure 4D appears below. The authors apologize for any…

CAMBRIDGE, England--(BUSINESS WIRE)-- #ADPD2024--bit.bio, the company coding human cells for novel cures, today announces the first project within a multi-year collaboration agreement with The Michael J. Fox Foundation for Parkinson's…

A total of 80% of the world’s primary energy comes from fossil fuels, of which the transportation sector uses a large amount . Approximately 10% of the world’s primary energy supply is made up of bioenergy. Bioenergy is expected to play…

1. IntroductionHuman herpesvirus (HHV) infections are widespread diseases that are benign in immunocompetent people but may lead to severe complications and occasionally to death in severely immunocompromised people. A decline in…

1. IntroductionGlobal sustainability represents one of the most relevant challenges that modern society has to face at present. The high dependence on fossil fuels has led humanity to an uncertain future due to the constant reduction…

A potentially alternative treatment for OA, a debilitating joint disease that affects more than 500 million people worldwide, is the regeneration of cartilage from…

Elevated markers of DNA damage in striatal neurons associated with OUD and chronic morphine in rhesus macaque. Credit: Nature Communications (2024). DOI:…

1. IntroductionThe utilization of vehicles powered by fossil fuels has led to a myriad of issues, including the escalation of global climate temperatures, emissions released into the atmosphere, and the depletion of conventional fuel…

In recent years, the scientific community has deeply investigated the effects of anthropic activities in terms of environmental pollution, as well as the consequences on human health, climate change and economics . Indeed, almost all…

1. IntroductionMutations in the epidermal growth factor receptor (EGFR) tyrosine kinase are observed in approximately 15% of NSCLC adenocarcinomas in the United States and occur more frequently in nonsmokers . In Asian populations, the…

5.1. Effects of Cytochalasins on Cytoskeletal Organization and Cell Morphology during OsteogenesisOsteogenic differentiation is a cellular process that involves specific cellular changes at both the structural and molecular level.…

Podcast FDA medical oncologists discuss the agency’s March 23, 2017,…

Podcast FDA medical oncologists discuss the FDA approvals of…

1. IntroductionDue to the existing paradigm, the transportation industry is facing a critical juncture regarding one of the most pressing issues that humanity needs to tackle. Worries about climate change have been rapidly increasing in…

Neurons that express Lag3 proteins (grey/white) can take in Tau proteins (red) compared with neighboring neurons that do not express Lag3. Credit: Xiaobo Mao, Johns…

Introduction Alzheimer’s disease (AD) is one of the most prevalent neurodegenerative diseases and the most common form of dementia (Winblad et al., 2016). AD leads to slowly progressive cognitive decline with impairment of memory,…

1 Background Parkinson’s disease (PD) is a progressive neurodegenerative disorder primarily characterized by the progressive loss of dopaminergic neurons in the substantia nigra and abnormal α-synuclein aggregation in Lewy vesicles…

In the report of this educational program, we focused on the evaluation of the expression of the predictive tumor response marker PD-L1 via the CPS score in a digital series of selected challenging cases of HNSCC. For each case, a board…

Podcast Cemiplimab FDA medical oncologists discuss the September 28,…