Cellular

NIH-supported study shows potential treatment pathway for neurodevelopmental disorder April 24, 2024 • Press Release In a proof-of-concept study, researchers…

TAD dynamics along p53 activation. Credit: Nature Communications (2024). DOI: 10.1038/s41467-024-46666-1 The simplest explanation of…

This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Submission received: 18 January 2024 / Revised: 4 March 2024 / Accepted: 16 March 2024 / Published: 30 March 2024 Abstract PRRS is a…

The underlying mechanisms of CIPN are not fully known, but they involve direct nerve damage, oxidative stress, inflammation, DNA damage, and microtubule dysfunction. Altered ion channel transmission, along with alterations in…

The authors would like to make the following corrections to this published paper .Upon reviewing Figure 3C (lane Y230), the authors observed a formatting error in the blot. Thus, Figure 3 should be replaced with the following version:…

Credit: CC0 Public Domain It's no secret that smoking is extremely detrimental to health. Tobacco smoke contains thousands of chemicals,…

Vaccines, Vol. 12, Pages 316: Unveiling a Shield of Hope: A Novel Multiepitope-Based Immunogen for Cross-Serotype Cellular Defense against Dengue Virus Vaccines doi: 10.3390/vaccines12030316 Authors: Nilanshu Manocha Daphné…

This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Open AccessReview by Shuo WangShuo Wang 1,*, Najla El JurdiNajla El Jurdi Dr. Najla El-Jurdi is an Assistant Professor of Medicine…

Cells rely on complex molecular machines composed of protein assemblies to perform essential functions such as energy production, gene expression, and protein synthesis. To better understand how these machines…

1 Introduction Population aging emerges as a pivotal phenomenon of our era, reshaping the demographic landscape. This shift in age distribution is poised to amplify age-related conditions, particularly dementia (World Health…

At a time in which scientific research is increasingly cross-disciplinary, Ernest Fraenkel, the Grover M. Hermann Professor in Health Sciences and Technology in MIT’s Department of Biological Engineering, stands…

Increased O-GlcNAcylation of cellular proteins is a characteristic feature of many types of cancer, including breast cancer. O-GlcNAcylation, considered as cellular metabolic sensor is closely linked to HBP flux, which is supplied by…

1. IntroductionThe constant evolution of SARS-CoV-2 due to spike (S) protein mutation is of great concern . Four years after the start of the first coronavirus pandemic, several SARS-CoV-2 variants were diversified to transmissibility,…

National Science FoundationDirectorate for Biological Sciences     Division of Molecular and Cellular Biosciences Full Proposal Deadline(s) (due by 5 p.m. submitter's local…

Biomedicines, Vol. 12, Pages 418: Epithelial-Mesenchymal Transition: A Fundamental Cellular and Microenvironmental Process in Benign and Malignant Prostate Pathologies Biomedicines doi: 10.3390/biomedicines12020418 Authors: Aviv…

1. IntroductionThe loss of mitochondrial function is a potentially important driver of aging and can limit the life and health span of mammals . One aspect of this loss is an increase in mitochondrial reactive oxygen species (ROS) as…

IntroductionThe phenomenon of aging is directly linked to a decline in cellular repair functions with an associated increase in aging phenotypes including genomic instability (Rando and Chang, 2012; Kennedy et al., 2014; López-Otín et…

1. IntroductionResponses to COVID-19 are variable: most SARS-CoV-2-infected individuals have mild or no symptoms, but in ~10–15% of cases COVID-19 patients progress to severe disease, in ~5% to critical disease and in ~1.3% to lethality…

2. LymphocytesCompared to myeloid cells, lymphocytes are much less numerous in gliomas, with an estimated frequency of 1–5% of all cellular tumor components . However, in contrast to their low numbers, they have an outstanding…