genes

CACNA1AR192Qrs121908211Gain of function, increased calcium influx and susceptibility to CSD and metabolic alterations.Migraine, FHM S218Lrs121908225Gain of function, increased calcium influx in the neuro system and led to hyper…

1. IntroductionLipids are essential for various cellular functions, including energy homeostasis, membrane remodeling, and lipid signaling . In plant cells, lipids are primarily found in the form of triacylglycerol (TAG), which is…

Credit: CC0 Public Domain People with specific genetic traits and those who have anxiety or depression have a significantly higher heart…

Smoking harms nearly every organ in the body and causes many diseases. Credit: CDC/Debora Cartagena Take a puff of nicotine for the first…

IntroductionIn beef production, the cost of feeding is a crucial factor that significantly impacts the overall cost of production. Studies have demonstrated that feed cost accounts for 60 to 70% of the total expenses in animal production…

IRP’s Susan Harbison Unravels the Genetics of Sleep DisordersBy Melissa GlimFriday, March 15, 2024 IRP senior investigator Susan Harbison is learning about sleep by examining and manipulating the genes of fruit flies.Comedian George…

Author ContributionsConceptualization, Q.W., J.L., B.L., W.-S.T. and X.L.; data curation, Q.W. and F.G.; formal analysis, Q.W., J.L. and L.Z.; funding acquisition, W.-S.T. and X.L.; methodology, Q.W., J.L., Q.Y., W.X. and F.G.; project…

Recent advances in gene editing technology could potentially be used to create disease-resistant animals. This could curtail the spread of avian influenza, commonly known as bird flu. In a recent gene editing study, my colleagues…

The regulation of gene expression is primarily achieved through cis-acting elements, and understanding how these elements are regulated by cellular signaling pathways is crucial for revealing the functions of these genes in different…

1. IntroductionAdventitious roots are produced from non-middle column sheath tissues such as stems or leaves of plants . The occurrence of adventitious roots is a critical factor for successful asexual propagation of plants. The…

1. IntroductionPhosphorus is a significant nutrient element for plant and soil microbial growth and development . Phosphorus in soils exists in both organic and inorganic forms, with organic phosphorus mainly comprising a mixture of…

Credit: Neuron (2024). DOI: 10.1016/j.neuron.2024.01.013 A new Northwestern Medicine study has found the immune system in the blood of…

1 Introduction Parkinson’s disease (PD) represents the fastest-growing neurodegenerative disease (Dorsey et al., 2018). PD is characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc),…

1. IntroductionWhile the World Health Organization (WHO) chief declared the end of the global health emergency for COVID-19 in 2023 (https://www.who.int/, accessed on 15 May 2023), numerous questions about this pandemic disease persist.…

Stanford researchers have gained new insights into how the rise of reproductive barriers between organisms creates new species and drives the incredible diversification of life on Earth. One major way that creatures become distinct from…

Multiple sclerosis is an autoimmune condition that occurs when the immune system starts attacking nervesKATERYNA KON/SCIENCE PHOTO LIBRARY The largest genetic database of ancient humans yet is shedding new light on…

Multiple sclerosis is an autoimmune condition that occurs when the immune system starts attacking nervesKATERYNA KON/SCIENCE PHOTO LIBRARY The largest genetic database of ancient humans yet is shedding new light on…

1. IntroductionProduced water (PW), the largest volume byproduct of the petroleum industry, is generated in the process of oil extraction . The composition of PW is complex, and it generally contains organic and inorganic compounds such…

Plant traits are determined by gene expression and environmental factors, which reflect the morphology, function, and adaptability of plants . Gene expression refers to the activity of genes at the transcriptional level, which determines…

Because of the diversity of PWWTPs, many physical/chemical/biological water parameters may affect the proliferation and fate of ARGs in PWWTPs. Redundancy analysis (RDA) was performed to confirm the relationship between the relative…

8.2. Overview of the Current State of Targeted TherapiesPituitary adenomas are linked with several related disorders, including prolactinoma, acromegaly, Cushing’s disease, and non-functioning pituitary adenoma. Treatment often requires…

Schematic illustration of evolutionary analysis to infer subtle regulatory shifts underlying human-specific single-cell transcriptomic divergence. Credit: Nature…

Sosnowsky’s hogweed (Moscow region, near the Sukhanovo estate). Credit: Anton Gladin For the first time ever, scientists have studied the…

The environmentally-regulated interplay between local three-dimensional chromatin organization and transcription of the osmoregulated proVWX operon in Escherichia…

Research supported by NIEHS and the National Institute of Allergy and Infectious Diseases (NIAID) may help to explain why some people with COVID-19 become severely ill while others have no symptoms at all, and why more men than women die…

Nearly 50 North Carolina-based scientists interested in the interplay of genetics and the environment gathered at the 2018 fall meeting of the North Carolina Genetics and Environmental Mutagenesis Society (GEMS), a regional scientific…

Replacing faulty genes with healthy ones has enabled several children with rare genetic disorders to have typical life experiences,…

Genes lost during vampire bats’ evolution may have helped them to adapt to their exclusive blood diet which is high in iron and fluid…