1. IntroductionAs functional units of heredity, plant genetic resources are genetic materials of actual or potential value and are important basic materials for genetic breeding . Better understanding of the genetic diversity and…
1. IntroductionThe Maedi-visna virus (MVV) and caprine arthritis-encephalitis virus (CAEV) belong to small ruminant lentiviruses (SRLV), a subgroup of viruses of the family Retroviridae which cause persistent and insidious infections in…
CACNA1AR192Qrs121908211Gain of function, increased calcium influx and susceptibility to CSD and metabolic alterations.Migraine, FHM S218Lrs121908225Gain of function, increased calcium influx in the neuro system and led to hyper…
In 2022, we reported the DNA sequences of 33 medieval people buried in a Jewish cemetery in Germany. Not long after we made the data publicly available, people started comparing their own DNA with that of the 14th-century German…
1. IntroductionPrince Rupprecht’s larch (Larix principis-rupprechtii Mayr) is a Pinaceae species native to northern China. Because of its durable qualities, robust resistance to harsh weather conditions, soil retention capability, and…
Saint Peter Saint Paul Archipelago (SPSPA)Saint Peter Saint Paul Archipelago, Brazil19offshorede Oliveira et al., 2019 Caribbean Offshore (CAO)Golfo de Morrosquillo, Córdoba Province, Colombia3offshoreCaballero et al., 2012 Ciénaga,…
“The big-picture question is how genetic variation leads to variation in appearance,” Barsh said.“This is a question that has all kinds of implications for different species, but we think that cats offer an especially tractable way…
The new Integrated Classifier Pipeline system uses genetic fingerprints to identify unintended bystander CRISPR edits. A confocal microscope image of an early…
1. IntroductionChina has the most extensive distribution of karst terrain globally, covering an area of 344 km2. The unique development process of karst landforms has resulted in the formation of distinctive landscapes, including peak…
YOUR life insurance company doesn’t care how much you think your life is worth, so long as you are prepared to pay a premium that covers your chosen sum. Instead, insurers are concerned with how likely it is that…
1. IntroductionUnderstanding the relationship between DNA sequence variation and the predisposition to common diseases has interested researchers for decades. In particular, after the initial release of the human genome , the number of…
Herbicide-resistant pigweed is a growing problem for farmersDesign Pics Inc / Alamy Stock Photo
A gene drive – a bit of DNA that cheats evolution and can spread even if harmful – has been successfully tested in a…
1. IntroductionGermplasm resources are essential for genetic research, enabling the exploration and utilisation of economically and ecologically important genes and traits . Therefore, it is crucial to collect, preserve, evaluate, and…
If you’ve ever had the pleasure of encountering Australia’s iconic magpies, you know these birds are intelligent creatures. With their striking black and white plumage, loud warbling voices and complex social behaviours, magpies…
News ReleaseThursday, March 7, 2024
NIH-led study sheds light on the causes of new cancers among childhood cancer survivors and could have implications for their screening and follow-upCommon inherited genetic factors that…
1. IntroductionIn December 2019, severe acute respiratory syndrome type 2 emerged as a pneumonia of unknown origin in Wuhan, Hubei Province, China. The pathogen was subsequently identified as SARS-CoV-2, and is responsible for causing…
When two parents each pass on a mutated copy of a particular gene to their baby, that child can get Pompe disease. Because this rare condition doesn’t affect you if you carry just one faulty gene, parents usually don’t realize they could…
Members of the rural family in Sopetrán, Colombia, where the researchers conducted their study of the paisa mutation that leads to Alzheimer's disease. Credit:…
Location of individuals and graves discussed in the text. Credit: Proceedings of the National Academy of Sciences (2024). DOI: 10.1073/pnas.2310545121…
The vocalizations of humans, bats, whales, seals and songbirds vastly differ from each other. But CMU and UC Berkeley researchers have found parts of the genome that…
IntroductionAccording to the most recent definition, aging is the process of molecular and cellular damage accumulation that leads to functional decline, chronic diseases, increased morbidity and mortality (Moqri et al., 2023). During…
As important components of ecosystems, enhancing the stress tolerance of trees is of significant importance for ecosystem stability and environmental protection. However, due to limitations imposed by natural selection and breeding…
News ReleaseMonday, February 19, 2024
Study details the unprecedented scale, diversity, and power of the All of Us Research Program.Researchers have discovered more than 275 million previously unreported genetic variants,…
News ReleaseTuesday, February 20, 2024
Improved genetic tests more accurately assess disease risk regardless of genetic ancestry.To prevent an emerging genomic technology from contributing to health disparities, a scientific…
Participants from Africa, Asia-Pacific, Latin America and the Caribbean joined workshops, organized by IDLO in The Hague, Guatemala and Bali, to explore legal frameworks for implementing the Nagoya Protocol.
The Nagoya Protocol, which…
1. IntroductionThe walnut genus (Juglans L.) consists of approximately 22 species , with species native to China , namely J. regia L., J. mandshurica Maxium, J. cathayensis Dode, J. sigillata Dode, and J. hopeiensis Hu. Among them,…
Platform of Genetic Research
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RSNY-A Beacon of Hope For Breast Cancer
Breast Cancer Prevention & Recovery
RSNY-Cancer Specialists
Investigating the Complex Network of Genes in Breast…
1 Background
Frailty, a common geriatric syndrome, is defined as an age-related state characterized by impaired biological reserves, a reduced ability to maintain physiologic homeostasis, and an increased vulnerability to adverse…
Following is a summary of current health news briefs.
Otsuka's drug for Alzheimer's disease agitation fails in late stage study
Japan's Otsuka Holdings said on Tuesday that its experimental drug failed to meet a…
Susceptibility assessment of ‘Draper’ × ‘Liberty’ Hybrids to AFR. A. Susceptibility of hybrids to AFR. Bars highlighted in orange represent the average fruit rot…
A team led by scientists from Scripps Institution of Oceanography at the University of California San Diego and the J. Craig Venter Institute (JCVI) has uncovered the genetic basis for the production of domoic acid, a potent neurotoxin…
When it comes to disease and health, which is more powerful—ZIP code or genetic code?
The degree to which nature and nurture affect disease and health remains one of the eternal—and still unanswerable—questions in medicine.…
IntroductionUnlike the essential fatty acids, linoleic acid (18:2n-6) and α-linolenic acid (18:3n-3), the concentration of oleic acid (18:1n-9) can readily be increased in bovine adipose tissue and muscle. Oleic acid is the most abundant…
A new Cell Reports paper from Bing Yao’s lab in Emory’s Department of Human Genetics provides insights into mechanisms underlying several neurodegenerative diseases, such as ALS (amyotrophic lateral sclerosis) and Alzheimer’s.It can be…
4.1. Crossing SystemThe mating system of the faveira-benguê tree provides valuable insights into the genetic dynamics and reproductive strategies of this species. These findings reveal significant details about mating preferences and…
Using data from the United States and Brazil, NIEHS grantees have unearthed the genetic basis for the production of guanitoxin, an important cyanotoxin produced by freshwater harmful algal blooms (HABs). Their findings could help…
3.1. Implications in the PrognosisPrognostic stratification for MF began with the development of the International Prognostic Scoring System (IPSS) in 2009, primarily based on clinical and laboratory features . As molecular genetic…
1. IntroductionOn a global scale, the rise in temperature causes unpredictable and challenging climate conditions and infertile habitats that rapidly affect the plant species inhabiting alpine regions . The sixth assessment report of…
January 18, 2024
• Research Highlight
Fragile X syndrome is a genetic disorder caused by the gene FMR1. It is the most common form of inherited intellectual…
1. IntroductionWheat (Triticum aestivum L.) is a crop essential to the world in general and Kazakhstan in particular, where it is important both for export and domestic consumption . In 2021, its harvest area reached 12.7 million…