liver

Overview of the study design. Credit: Life Science Alliance (2024). DOI: 10.26508/lsa.202302517 In the largest study of its kind,…

In response to chronic stimuli such as alcohol abuse, viral infection, NAFLD/NASH and toxic damage, liver loses its normal structure and non-parenchymal cells…

MOF materials efficiently enrich circulating nucleic acids (cfDNA and cfRNA) in blood through a simple operational process, enabling various downstream nucleic acid…

1. IntroductionVaccinations have transformed public health, notably since the 1960s, when national vaccination programs were established. According to World Health Organization data, vaccination programs prevent 2–3 million deaths each…

1. IntroductionCardiovascular diseases (CVD) represent a major concern in preventive health. An estimated 17.9 million people died from CVDs in 2019, representing 32% of global deaths worldwide. Of these deaths, 85% were due to heart…

Credit: Unsplash/CC0 Public Domain For Latinx kids, unreliable access to food at age 4 raises the odds of having fatty liver disease later…

Credit: Molecular Systems Biology (2024). DOI: 10.1038/s44320-024-00024-x New research from Karolinska Institutet shows how estrogen…

1. IntroductionLiver transplantation is the treatment of choice for end-stage liver disease. Since the first successful liver transplant in 1967, the survival rate has improved considerably . Despite numerous developments in surgical…

Media AdvisoryTuesday, March 5, 2024 NIH-funded findings inform interdisciplinary care approach across the lifespan.What A weekly injection of semaglutide was safe and reduced the amount of fat in the liver by 31% in people…

3.4. Meta-Analysis: The Pooled Effects of TelemedicineOut of the five included studies, three were included in the meta-analysis, while two studies were conducted with single-arm designs. Three studies (Lim et al., Policarpo et al.,…

Credit: CC0 Public Domain A University of Cincinnati Cancer Center study has found that real-time navigation is a useful tool for surgeons…

The human gut microbiota (GM) consists of bacteria, viruses (including phages), fungi, and primitive prokaryotic Archaea that reside in the digestive tract. They possess many genes, outnumbering those of their human host by one hundred.…

1. IntroductionReaching an estimated global prevalence of 25% , metabolic dysfunction-associated steatotic liver disease (MASLD) is the leading cause of chronic liver disease and an emerging risk factor for cirrhosis and hepatocellular…

Backgrounds Factors in Each GroupTable 1 shows the backgrounds of patients in each group. All values—tumor number, tumor size, and indocyanine green 15-min retention (ICGR15)—are the medians from the group.The median values of tumor…

1. IntroductionEchinococcus granulosus is a tapeworm that, in its larval stage, causes hydatid disease. Hydatidosis is an endemic condition prevalent in geographic areas such as the Middle East, Asia, sub-Saharan Africa, the…

1. IntroductionSerotonin (5-hydroxytryptamine, 5HT) is a biologically active amine present in the central nervous system (CNS) and the peripheral tissues of mammals. In the “central 5HT compartment”, it is best known as a…

1. IntroductionSepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection, often resulting in severe multiorgan failure with a high mortality rate of 25–30% . According to the Sepsis-3 consensus…

​Glyphosate, the primary ingredient in Monsanto’s popular weed killer Roundup, has been linked to liver disease in animal models. In a new study, the first of its kind, researchers at the University of California…

About the Mount Sinai Health System Mount Sinai Health System is one of the largest academic medical systems in the New York metro area, with more than 43,000 employees working across eight…

1. BackgroundThe colorectal cancer (CRC) incidence rate is growing. It is the third most common and second deadliest malignancy worldwide, with more than 1.9 million new cases and 935,000 cancer-related deaths annually . Recent…

MIT biological engineers have created a multitissue model that lets them study the relationships between different organs and the immune system, on a specialized microfluidic platform seeded with human cells.…

You have often heard “You are what you eat,” but according to research from Baylor College of Medicine, the new phrase could be “You are what you are exposed to.” New research shows that, in animal models, the liver epigenome is…

Article Content In mouse studies, researchers at University of California San Diego School of Medicine report that lactating mothers expose their feeding pups to triclosan, an antimicrobial commonly used in consumer…

Looking back, John Groopman, Ph.D., sees the scientific backdrop of 1950s America as a catalyst for his career. The Space Race was underway, and in 1957, just before he began elementary school, the U.S. helped launch the International…

Researchers at the University of California (UC), San Diego found evidence that newborn mice can be exposed to triclosan during lactation, resulting in significant fat build up in their liver — an early sign of liver damage. The study…

A large-scale study on exposure to per- and polyfluoroalkyl substances (PFAS) in humans and rodents showed consistent evidence of chemical-driven liver damage, according to NIEHS grantee Lida Chatzi, M.D., Ph.D., from the University of…

1. IntroductionCurrently, water pollution is becoming a global challenge that increasingly threatens human and environmental health . In fact, rapid industrialization, domestic effluents from human settlements, and modern agriculture…

Stained tissue from mice with experimental liver fibrosis (top) compared to liver tissue from normal mice (bottom). Credit: Bawendi laboratory, Massachusetts Institute of Technology Department of Chemistry.Chronic liver diseases such as…

1. IntroductionTrauma is a substantial global public health issue and a leading cause of death, hospital admissions, and long-term disability during the first four decades of life. Additionally, it ranks among the primary causes of…

Three experts from the academic and private sectors presented emerging technologies that could provide biologically relevant alternatives to animal testing at a Jan. 30 webinar organized by the National Toxicology Program Interagency…

Presently, at least five distinct genetic variants are strongly linked with an increased susceptibility to MASLD progression. These variants are in PNPLA3, TM6SF2, GCKR, MBOAT7, and HSD17B13 genes . Some of these genetic variations also…

1. IntroductionHepatic osteodystrophy is the generic term defining the group of metabolic bone diseases, including osteoporosis and osteomalacia, which appear as possible complications of chronic liver disease .Osteoporosis is very…

In recent years, the fusion of radiomics and machine learning has yielded promising results in the evaluation of treatments for malignant liver tumors (e.g., surgical resection, liver transplant, ablation therapy, transarterial…

Did you know that type 2 diabetes and overweight can put you at an increased risk for certain types of liver disease? Research is starting to reveal more about this often-overlooked connection between type 2 diabetes and your liver.…

Credit: Pixabay/CC0 Public Domain Those who binge drink and have a certain genetic makeup are six times more likely to develop…

Other Names for Added SugarAccording to the Food and Drug Administration, added sugars include sugars that are added during the processing of foods (such as sucrose or dextrose), foods packaged as sweeteners (such as table sugar), sugars…

It is still unclear what is behind a worrying surge in cases of liver disease among young children in several countries, but a lack…

Here’s a type of hepatitis you probably haven’t heard of before. Like all types of viral hepatitis, hepatitis E is a disease that affects the liver. It is spread by ingesting fecal matter contaminated with hepatitis E virus, even in…

Hepatitis C is a liver disease caused by the hepatitis C virus (HCV). It is spread through exposure to blood, often as a result of injection drug use. Less commonly, hepatitis C is spread through sex or from an infected mother to her…

After completing a human trial of modified pig skin grafts last year, a team in China hopes to start the first pig organ transplant…