DNA

The digital reconstruction of Emperor Wu's face (left), alongside a painting made of him from the 'Thirteen Emperors Scroll' (right). Pianpian…

Scientists genetically analysed stored blood samples collected during the Penn Medicine BioBank studyDaniel Burke Photography/Penn Medicine BioBank Being in intensive care is bad enough, but it can be even worse if…

In 2022, we reported the DNA sequences of 33 medieval people buried in a Jewish cemetery in Germany. Not long after we made the data publicly available, people started comparing their own DNA with that of the 14th-century German…

Credit: Unsplash/CC0 Public Domain New DNA sequencing technologies have identified the historical remains of George Washington's…

YOUR life insurance company doesn’t care how much you think your life is worth, so long as you are prepared to pay a premium that covers your chosen sum. Instead, insurers are concerned with how likely it is that…

IntroductionCellular senescence is a ubiquitous process and is a state of irreversible cell cycle arrest, induced by a variety of cellular stimuli such as DNA damage, telomere shortening/dysfunction, oncogenic activation and chromatin…

Maggi et al. (2010) Four patients with acute leukemiaBefore total body irradiation (TBI) and after allo-SCT (within the first 30 days; in 2 patients at days +50, +80, and +110 after transplantation)All patients (n = 4) developed plasma…

The Molecular Ecology Laboratory applies genetic and genomic technologies to address a variety of complex questions and conservation issues facing the management of the Nation's fish and wildlife resources. Together with…

For some dog DNA tests, companies require pet owners to upload a photograph of the pet with the DNA sample. In other tests the photo can be optional. This photo of…

Breakdown of each study arm. Credit: Scientific Reports (2024). DOI: 10.1038/s41598-024-55105-6 A U.K. trial has found a DNA-tailored diet…

In the 1970s and 1980s, pine trees growing in various forestry plantations in South Africa’s Western Cape province began to die in patches. These trees succumbed to a mysterious root disease and the patches expanded gradually.…

People in India have a wide range of Neanderthal DNA in their genomesDebajyoti Chakraborty/NurPhoto via Getty Images The largest ever genome study of South Asian people has discovered a wide range of Neanderthal DNA…

IntroductionAging is a time-dependent general loss of functionality and fitness across lifespan, and the parallel accumulation of molecular damages, including altered epigenomic regulation is considered one of the key hallmarks of aging…

Credit: CC0 Public Domain Smoking changes the way genes are expressed, which later contributes to the development of lung cancer and other…

Credit: CC0 Public Domain People living in ancient Eastern Arabia appear to have developed resistance to malaria following the appearance of…

Elevated markers of DNA damage in striatal neurons associated with OUD and chronic morphine in rhesus macaque. Credit: Nature Communications (2024). DOI:…

1. IntroductionIncreasingly, studies are linking air pollution to an increased risk of adverse pregnancy outcomes such as preterm birth (PTB) . Among these pollutants, volatile organic compounds such as BTEX (benzene, toluene,…

The robot has a gold and iron core and is surrounded by a gold cage. DNA serves as its clutch.Jinwoo Cheon A nanoscale robot with a clutch can engage or disengage its engine, allowing for more precise control over…

1. IntroductionRetroviral infection begins with the reverse transcription of the RNA genome in the cytoplasm to form linear double-stranded DNA that will soon be delivered into the nucleus . A portion of this linear DNA gives rise to…

Caves and rock shelters dot the mountains in the northwestern highlands of Thailand. Over 40 in Mae Hong Son province contain wooden coffins on stilts, dating back…

This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Int. J. Mol. Sci. 2024, 25(3), 1891; https://doi.org/10.3390/ijms25031891 (registering DOI) Submission received: 14 December 2023 /…

Long-term space exploration exposes humans to radiation that can damage deoxyribonucleic acid or DNA, which carries the genetic information for our development and functioning. Conditions in space also affect the way the body repairs…

1. IntroductionType 2 diabetes mellitus (T2DM) is characterized by increased insulin resistance (IR), insulin insensitivity, and blood glucose levels and is becoming increasingly prevalent worldwide . Under normal conditions, blood…

An international team led by scientists at the National Institutes of Health is the first to discover a new way that cells fix an important and dangerous type of DNA damage known as a DNA-protein crosslink (DPC). The researchers found…

Emory University researchers have learned that exposure to Polybrominated Biphenyl (PBB), an endocrine-disrupting fire-retardant, is associated with epigenetic marks, which affects the way genes are expressed. Their findings show that…

The team wondered how much of that diversity was unique to Rome, the capital of the empire, and how diverse more remote areas might have been. In the study, they focused on a narrower window of time — from the conclusion of the Iron…

Spider webs capture airborne DNAVechterova Valeria/Shutterstock Elephants, giraffes and rhinos can all be caught in spider webs – or at least their DNA can. Josh Newton at Curtin University in Western Australia…

Spider webs capture airborne DNAVechterova Valeria/Shutterstock Elephants, giraffes and rhinos can all be caught in spider webs – or at least their DNA can. Josh Newton at Curtin University in Western Australia…

IntramuralBy Janelle Weaver New approach detects authenticity of botanical dietary supplements A chemical analysis workflow that combines two…

Using a virus-like delivery particle made from DNA, researchers from MIT and the Ragon Institute of MGH, MIT, and Harvard have created a vaccine that can induce a strong antibody response against SARS-CoV-2. The…

7/22/2019 PITTSBURGH – In the time it takes you to read this sentence, every cell in your body suffers some form of DNA damage. Without vigilant repair, cancer would run rampant, and now scientists at the University of…

​Causes of cancer are being catalogued through an international study revealing the genetic fingerprints of DNA-damaging processes that drive cancer development. Researchers from University of California San…

Over the past several decades, most people have come to understand what DNA is – generally, it's defined as the carrier of a person's distinct genetic information. Since DNA was first used in forensic science in the late…

IntroductionThe phenomenon of aging is directly linked to a decline in cellular repair functions with an associated increase in aging phenotypes including genomic instability (Rando and Chang, 2012; Kennedy et al., 2014; López-Otín et…

Chromatin is the structure inside our cell nuclei that organises DNA like knitting organises wool into a scarf. If a strand of DNA from a single cell were uncoiled into a straight line then the length would be two metres long. That is…

The NER (nucleotide excision repair) mechanism is employed to repair the damage by creating large adducts and intra-strand crosslinks when UV light and polycyclic aromatic hydrocarbons damage DNA. The nucleotide excision respirasome, a…

DNA methylation is an important form of an epigenetic modification widely found in plant genomes, and it regulates the expression of genes in various developmental periods, as well as in different plant tissues . There are three main…

Improved understanding of factors driving DNA damage and repair may offer new clues for personalized disease prevention, according to Bevin Engelward, Sc.D., a biological engineer and director of the Superfund Research Program at the…

2.1. Study Design and Baseline Screening ProcedureBetween June to August in 2018, a total of 2000 women aged 25–64 from Tuoli County, Xinjiang, China, were recruited to this prospective cervical cancer screening cohort study. Details on…

How the body repairs DNA damage following exposure to a chemical called N-nitrosodimethylamine (NDMA) can provide new insights for cancer treatment, according to Jennifer Kay, Ph.D. The former NIEHS Superfund Research Program (SRP)…

Ryan McRae and Briana Pobiner The year 2023…

Research into how toxicants may cause DNA damage that accelerates aging, methods to identify early signs of cancer, new scientific tools to better understand gene-environment interactions, and the health effects of exposure to light were…

Meilan Solly Associate…

Today's ice sheet in Antarctic and that during the Last Interglacial when seaways allowed connections between octopus populations. Scientists…

Turquet’s octopus David Barnes via the University of Western Australia In the sea surrounding…

Early detection of infectious diseases can be key to successful treatment, but we often don’t know we are infected until symptoms appear. What if our bodies could detect the presence of an infectious pathogen before the onset of disease?…

December 18, 2023 Two University of Wollongong (UOW) researchers, Dr Jacob Lewis and Dr Dezerae Cox, have been awarded Investigator Grants worth more than $1.2 million by the National…

Scientists use electricity to make cells take up DNA – and the same process could happen in nature thanks to electric eels’ shocking powers

A Stanford Medicine-led, international study of hundreds of samples from patients with Hodgkin lymphoma has shown that levels of tumor DNA circulating in their blood can identify who is responding well to treatment and others who…

DNA can be used to make nanomachinesKiyoshi Takahase Segundo/Alamy Nanoscale “robots” made of DNA that rapidly self-replicate could be harnessed to manufacture drugs or other chemicals inside the body, say…