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SILDENAFIL

DailyMed – SILDENAFIL tablet – Inergency

SUPER-1 (NCT00644605) -sildenafil tablets monotherapy A randomized, double-blind, placebo-controlled study of sildenafil tablets (SUPER-1) was conducted in 277 patients with PAH (defined as a mean pulmonary artery pressure ≥25 mmHg…

DailyMed – SILDENAFIL tablet

SUPER-1 (NCT00644605) -sildenafil tablets monotherapy A randomized, double-blind, placebo-controlled study of sildenafil tablets (SUPER-1) was conducted in 277 patients with PAH (defined as a mean pulmonary artery pressure ≥25…

DailyMed – SILDENAFIL tablet, film coated

12.1 Mechanism of Action Sildenafil is an inhibitor of cGMP specific PDE-5 in the smooth muscle of the pulmonary vasculature, where PDE-5 is responsible for degradation of cGMP. Sildenafil, therefore, increases cGMP within…

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