Understanding CDC’s Latest COVID-19 Isolation Guidance

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The Centers for Disease Control and Prevention (CDC) updated their COVID-19 isolation guidance, revising the minimum 5-day isolation period plus added precautions for those that are infected with the virus. Now, the guidance for those infected with COVID-19 as well as for influenza and Respiratory Syncytial Virus (RSV) encompasses a two-pronged approach:
 

Stay-at-home period: Stay home and away from others until at least 24 hours after BOTH your symptoms (i.e., cough, runny nose, chills, see full list here.) improve AND you no longer have a fever (>100.4°F) without the use of fever-reducing medication like Tylenol. 
Post-24-hour isolation period precautions: After the 24-hour period of being fever-free and other symptoms have improved, continue to take added precautions over the next 5 days to prevent viral spread to others including wear a high quality, well-fitting mask, keeping a distance from others, practicing respiratory etiquette and hygiene practices (wash hands), getting tested for respiratory viruses, and seeking well-ventilated spaces.

The change in CDC guidance is attributed to three primary factors: 
 

1. Vaccination Availability and Effectiveness: COVID-19 vaccines have shown to reduce the risk of severe disease by at least 50% and are broadly accessible across the U.S.
 

2. Treatment Availability and Effectiveness: Treatment like Paxlovid have demonstrated the ability to reduce the likelihood of hospitalization by more than 50% and decreases the risk of mortality even further, by 75%. 
 

3. Population Immunity: Over 98% of the U.S. population is estimated to have acquired some level of protective immunity, either through vaccination, prior infection, or both.
Despite a notable decline in morbidity and mortality from COVID-19, with it moving from the 3rd   leading cause of death in 2020 and 2021 to the 10th currently, the virus continues to pose a significant public health challenge. This is especially true for high-risk groups, such as older adults, young children, individuals with compromised immune systems, people with disabilities, and pregnant individuals. Furthermore, the condition of long COVID, a consequence of initial and subsequent infections, remains a critical public health concern.
 

Remaining up to date with your covid-19 vaccination remains a crucial and core prevention strategy to (1) lower your risk of getting infected, (2) lower your risk of experiencing long-covid, and (3) lowering your risk of severe illness, hospitalization, and death from COVID-19. Let’s also not forget the simple yet profound impact of mask-wearing, particularly when you are sick and in close contact with others as it can reduce the spread of COVID-19 and other respiratory viruses, preventing further onward spread to those around us.

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