Acute

2. Materials and Methods 2.1. Study PopulationThis single-center, retrospective study enrolled all consecutive patients with HF undergoing ICM invasive procedures at Careggi University Hospital from January 2019 to December 2023,…

1. IntroductionHypertension is a significant risk factor for stroke with a 10% increase in its prevalence being correlated with an almost three-fold higher stroke incidence at the population level . However, the elevated blood pressure…

1 Introduction The diagnosis of Parkinson's disease (PD)relies on clinical assessments of cardinal motor symptoms such as bradykinesia, rigidity, tremor, and postural instability. Ocular movements in this patient population, however,…

Israel says it will send a delegation to Qatar for more talks with mediators after Hamas presented a new truce proposal.The main United Nations aid agency operating in Gaza has said that acute malnutrition was accelerating in the north…

1. IntroductionAcute promyelocytic leukemia (APL) accounts for 10% of all cases of acute myeloid leukemia (AML) . This specific subtype of acute leukemia is distinguished by a high potential for cure using regimens that involve…

1. IntroductionIf unrecognized, Charcot neuro-osteoarthropathy (CNO) can be a destructive and devastating complication of neuropathy in patients affected by diabetes, as it can lead to joint and bone deformities, development of ulcers…

A new study published by the Centers for Disease Control and Prevention (CDC) today, “Acute Hepatitis and Adenovirus Infection Among Children — Alabama, October 2021–February 2022” provides additional clinical and epidemiologic…

5.1. Perivascular Macrophages (PVMs)Perivascular macrophages (PVMs) are a unique subset of interstitial macrophages that inhabit the perivascular spaces of various tissues, including the lungs . These specialized macrophages occupy a…

1. IntroductionA substantial number of patients with COVID-19 continue to experience lingering symptoms. Studies estimate that approximately 1 out of 5–8 people who have had COVID-19 may develop Long COVID-19 . Observational evidence…

Tet2-deficient macrophages are hyperinflammatory in early ischemic kidney injury. Credit: Nature Medicine (2024). DOI: 10.1038/s41591-024-02854-6…

The Centers for Disease Control and Prevention (CDC) continues to work with health departments and clinicians nationwide to identify and investigate hepatitis of unknown cause impacting children. As of today, 36 states and territories…

Gene frequencies of the CYP7A1 gene polymorphisms in ACS patients and the controls were in Hardy–Weinberg equilibrium. Only two polymorphisms (rs3808607 G/T and rs1457043 C/T) out of the seven polymorphisms studied in this work were not…

Posted on March 7th, 2024 by Dr. Monica M. Bertagnolli The protein Sox9 switches on…

1. IntroductionArticular cartilage within a joint provides a low-friction gliding surface while also acting as a shock absorber and reducing peak pressures to the subchondral bone . An acute articular cartilage tear is an injury…

1. IntroductionVenous thromboembolism (VTE), including deep venous thrombosis (DVT) and pulmonary embolism (PE), ranks as the third most common cardiovascular ailment after myocardial infarction and stroke . The risk of VTE doubles with…

This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Biomedicines 2024, 12(3), 580; https://doi.org/10.3390/biomedicines12030580 (registering DOI) Submission received: 31 January 2024 /…

The FDA, along with the CDC and the Southern Nevada Health District, investigated a number of reports of acute non-viral hepatitis in the state of Nevada associated with “Real Water” brand alkaline water. Real Water Inc. is not…

1. IntroductionFrailty is a common syndrome, predominantly affecting older people, that can be described as a multi-factorial, age-associated decline in the ability to manage stressors, which predisposes vulnerable, at-risk individuals…

In this study, we investigated the impact of (C. fumosorosea mycelia, cockroaches), their combination (MIX) on lung health and serum metabolites in a mice model of (LPS) acute lung injury (ALI). Inflammation can be described as the…

Discussion The biannual peak pattern of AFM cases observed during 2014–2018 did not persist in 2020 or 2022. In 2020, nonpharmaceutical interventions for prevention of COVID-19 likely reduced the number of EV-D68 and other respiratory…

Podcast FDA medical oncologists discuss the Aug. 3, 2017, approval…

General Osterlund et al., 2014 Uganda—small-scale vegetable farms; 317 farmers; APP case count not specifiedWHO Classes I, II, III, U—mostly Class IIInterview and questionnaire assessing knowledge, attitudes, symptoms, hygiene, and…

Podcast IDH1 FDA medical oncologists discuss the July 2018 approval…

1. IntroductionThe severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) known as Coronavirus disease 2019 (COVID-19) emerged in Wuhan, Hubei province, China in December 2019 . The latest reports from WHO have shown 767,750,853…

3. DiscussionTo the best of our knowledge, a literature review of aortic pathologies type, reperfusion therapy type, and the complication of both mechanical thrombectomy and local transbrachial approach in patients with acute ischemic…

CINCINNATI--(BUSINESS WIRE)--Headline of release should read: Acute Myeloid Leukemia (instead of Acute Myeloid Lymphoma). The updated release reads: KUROME THERAPEUTICS ANNOUNCES FDA CLEARANCE OF INVESTIGATIONAL NEW DRUG (IND)…

CINCINNATI--(BUSINESS WIRE)--Kurome Therapeutics Inc. is pleased to announce that the U.S. Food and Drug Administration (FDA) has cleared the IND for KME-0584, allowing the company to proceed with a Ph1 clinical trial in…

This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Open AccessReview by , , Christina-Nefeli Kontandreopoulou and Panagiotis Τ. Diamantopoulos * Hematology Unit, First…

Disclaimer: Early release articles are not considered as final versions. Any changes will be reflected in the online version in the month the article is officially released. Author affiliations: Children’s Hospital…

1. IntroductionAortic dissection involving the ascending aorta and/or the aortic arch, defined as type A aortic dissection according to the Stanford classification, remains an acute, critical pathology requiring emergent surgical…

COVID, Vol. 4, Pages 221-260: Differential Diagnosis in the Management of Acute Respiratory Infections through Point-of-Care Rapid Testing in a Post-Pandemic Scenario in Latin America: Special Focus on COVID-19, Influenza, and…

IJERPH, Vol. 21, Pages 193: Real-Time Epidemiology and Acute Care Need Monitoring and Forecasting for COVID-19 via Bayesian Sequential Monte Carlo-Leveraged Transmission Models International Journal of Environmental Research and Public…

AML is one of the neoplasms that benefit from DC-based therapies, specifically through the administration of the vaccines mentioned in the previous section.AML is a blood cancer characterized by the uncontrolled growth of abnormal…

1. IntroductionThe reduction in low-density lipoprotein cholesterol (LDL-C) leads to fewer cardiac risks in patients with atherosclerosis and cardiovascular disease . Moreover, a favorable biological effect of statins not only on LDL-C…

1. Introduction, Background, and Mission SpaceIn December 2019, a novel coronavirus disease (COVID-19) emerged in Wuhan, Hubei province, China . A cluster of patients with severe respiratory illnesses, such as viral pneumonia and lung…

Protocol on lung USLichtenstein DA and Mezier GA, 2008 FranceObservational study 301Asmara OD et al., 2022 IndonesiaSystematic review and meta-analysis Dexheimer Neto FL et al., 2015 BrazilObservational study 42Patel CJ et al., 2018…

Introduction Frailty occurs in approximately one-quarter of all patients (Taylor-Rowan et al., 2019) and is common in older people and is associated with increased mortality, long-term hospitalization, and disability (Mathers et al.,…

1. IntroductionFollowing acute myocardial infarction (AMI), myocardial stretch due to increased mural stress at the infarct site activates a cascade of processes in myocytes and the extracellular matrix. The necrotic tissue activates an…

A total of 21 ICU nurses were interviewed (Table 3). The mean age was 34.04 years, SD = 7.4. Regarding sex, 71.4% were female and 28.6% male. Regarding marital status, 33.3% were married, 4.7% divorced, and 62% single. In total, 62% of…

Disclaimer: Early release articles are not considered as final versions. Any changes will be reflected in the online version in the month the article is officially released. Author affiliations: The University of…

1. IntroductionThe central dogma of molecular biology was first presented by Francis Crick in a lecture in 1957, where he stated that deoxyribonucleic acid (DNA) is transcribed into ribonucleic acid (RNA) and RNA is translated into…

3.1. Serologic BiomarkersIt is crucial to highlight that any single serologic marker is not sufficient to detect risk for hemodynamic collapse and must be considered within the context of clinical history, baseline comorbid conditions,…

1. IntroductionAcute lymphoblastic leukemia (ALL) is the most common pediatric cancer, comprising approximately 25% of new cancer diagnoses in those under the age of 15 . Childhood ALL represents a model treatment paradigm for pediatric…

1. IntroductionCOVID-19 is an acute respiratory infectious illness caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which emerged in 2019 in the Wuhan region of China and rapidly spread to various parts of…

Jeanne C. Ruff, MSN, MPH1,2,3; Ying Zhang, PhD3; David P. Bui, PhD2,4; Colin Therriault, MD4; Daniel Nogee, MD4,5; Stephen L. Guthery, MD6,7; Johnni Daniel, DHSc4 (View author affiliations) View suggested citation…

Melisa M. Shah, MD1,2; Ariana Perez, MPH1,3; Joana Y. Lively, MPH1; Vasanthi Avadhanula, PhD4; Julie A. Boom, MD4,5; James Chappell, MD, PhD6; Janet A. Englund, MD7; Wende Fregoe8; Natasha B. Halasa, MD6; Christopher J. Harrison, MD9;…

Figure 1. Patient cohort for data analysis. Figure 1. Patient cohort for data analysis. Figure 2. Changes in hemodynamics and LVEF in the overall cohort. In the overall cohort, no significant changes in cardiac output (CO),…

*Number of countries reporting data can vary between reporting weeks. In week 48, 4 (Ireland, Germany, Malta, Spain) countries reported data for SARS-CoV-2 shown in the figure above. Note that data from Ireland is for cases ≥15 years of…

On June 14, 2022, this report was posted online as an MMWR Early Release.Anita K. Kambhampati, MPH1; Rachel M. Burke, PhD1; Stephanie Dietz, PhD2; Michael Sheppard, MS2; Olivia Almendares, MSPH1; Julia M. Baker, PhD1,3; Jordan Cates,…

On June 24, 2022, this report was posted online as an MMWR Early Release.Jordan Cates, PhD1,*; Julia M. Baker, PhD1,2,*; Olivia Almendares, MSPH1; Anita K. Kambhampati, MPH1; Rachel M. Burke, PhD1; Neha Balachandran, MBBS1,3; Eleanor…